Many studies have pointed out that fermented black garlic has anti-cancer, anti-obesity, hepatoprotective and anti-inflammatory properties. However, current information on these biologically active ingredients or compounds remains unclear. Therefore, the purpose of this study was to investigate the protective effects of five different polar solvent black garlic extracts on carbon tetrachloride-induced liver injury. The results showed that black garlic had a significant improvement effect on acute liver injury induced by carbon tetrachloride, which not only improved the antioxidant activity, but also reduced the inflammatory response, providing a pharmacological basis for clinical application.

Black Garlic; Carbon Tetrachloride; Hepatoprotective Effect; Antioxidant Effect